Uzbekistan Introduces Advanced Immunotherapy for Insect Bite Allergies

Tashkent, Uzbekistan (UzDaily.com) — Uzbekistan has become the third country in the world to implement a new method of allergen-specific immunotherapy (ASIT) to treat severe allergic reactions to insect stings, the Ministry of Health of the Republic of Uzbekistan reported.

According to research, anaphylactic shock occurs in 20–30% of cases following stings from bees, wasps, hornets, bumblebees, and ants. Without urgent medical intervention, such reactions can be life-threatening.

For the first time in Central Asia, patients are receiving treatment at the Republican Specialized Center for Allergology and Clinical Immunology using a new immunotherapy drug based on bee venom.

“Allergic reactions to insects most often develop in adults after stings from winged insects. Severe reactions manifest as weakness, pale skin, itching, angioedema, and a sharp drop in blood pressure,” explains Professor Ilmira Razikova, head of the center.

The therapy involves gradually administering small doses of the allergen solution to the patient. This process reduces levels of specific IgE antibodies, increases blocking IgG4 antibodies, alleviates symptoms, and prevents potentially fatal anaphylactic reactions.

Previously, similar therapy had been applied only in Georgia and Türkiye.

The introduction of this method in Uzbekistan has attracted global medical attention and opens new opportunities for preventing severe allergic conditions in Central Asia.